Regarding the watchdog stuff:
... trim ...
However many SFP modules are "bad at I2C-ing", holding the bus seized/blocked for long amounts of time.

Sounds plausible. I will procure some MikroTik native copper SFP+ transceivers and see if that makes a difference.

Just upgraded from 7.16.2 hoping to kill a problem with watchdog timer reboots on my CRS328-24P-4S+. Started using my SFP+ ports after getting fiber internet (capable of 5Gb/sec, set up for 2Gb/s). I have three 10Gb copper SFP+ inserts and have discovered that almost any link down event on them will...

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.... TRIM ....
/interface bridge settings set allow-fast-path=no
.... TRIM ....

Pretty sure that is your problem.