Some of the RouterBOARDs, like [big] LtAP, have miniPCIe and USB 3.0. I know how the LTE works on miniPCIe & know Mikrotik does make miniPCIe Wi-Fi modules... Just never tried using their miniPCIe for Wi-Fi – even with the "newer" R11e-5Hxxx modules.
Whether any Wi-FI 6 card work would depend a lot on the drivers Mikrotik loads I guess. But google found tons of 802.11ax miniPCIe things – but imagine most need some custom driver or expect root access to compile etc etc etc. Certainly you'd need external antennas etc. for MIMO, etc., etc.
Not looking to blaze a new path myself for 802.11AX using miniPCIe. But curious if anyone has tried to use some 3rd party miniPCIe modules that supports 802.11AX / Wi-Fi 6?