Where to begin...
Out of the box (or after a hard reset) a RB750GL is configured as a firewall router with a public WAN side on port 1 and private LAN side on ports 2-5.
This is obviously only a partial match for your situation. On the other hand you still have a WAN input coming from the ADSL modem and you should firewall and treat that as such. In part that means that you should have a firewall between the ADSL modem and your PC and you should have the untrusted clients on one or more other ports. Something like this:
modem -----+ firewall +----- your "management" pc
+----- untrusted client 1
+----- untrusted client 2
+----- untrusted client 3
Here the modem would be connected to port 1, management to port 2 and so on. You might want to remove all the ports from the switch group to isolate clients from each other, and definitely would want to remove your PC from it.
Another option would be to use port 1 WAN, port 2 your personal LAN, and hang a managed switch like a RB250GS off port 3 to handle client traffic. (Using that you can again isolate the clients from each other).
Fewi has a excellent configuration tutorial which discusses setting up a DMZ which is only a little different than setting up an untrusted client zone.
http://wiki.mikrotik.com/wiki/How_to_co ... ome_router