i have two mikrotik at two different place
and two MT connect to internet with regesred ip

MT1:
ip address eth1 80.191.191.191(valid) on ISP X
ip addrees eth2 192.168.141.0/24

MT2:
ip address eth1 85.9.9.9(valid) on ISP Y
ip addrees eth2 192.168.0.0/24

how i can ping 192.168.0.1 to 192.168.141.1?
please step by step.
thanx.

You can use VPN. For example, a PPTP tunnel http://www.mikrotik.com/testdocs/ros/3.0/vpn/pptp.php . This link also provides step by step example you need.